Side Effects of Symbicort (Budesonide And Formoterol)

Symbicort is a prescription medication that combines budesonide and formoterol. Symbicort is used in the treatment of asthma when the condition is severe or when previous treatments have not been adequate. Symbicort comes in the form of an inhaler and helps to improve lung function and ease breathing. The side effects of Symbicort are often rough and include sour stomach, difficulty sleeping, and headache.

The two main components of Symbicort, budesonide and formoterol, are in two different classes of drugs that treat symptoms of asthma. Budesonide is a corticosteroid; its primary function is to ease inflammation and swelling. Formoterol is a bronchodilator; its purpose is to relax the airways to improve breathing. According to the Mayo Clinic, Along with asthma, Symbicort is sometimes prescribed to treat chronic obstructive pulmonary disease, or COPD.

Among the most common moderate symptoms of Symbicort are indigestion, acid reflux, nausea, and burping. Additionally, muscle spasms or muscle stiffness can develop. Throat irritation, hoarseness, and a dry cough are also common side effects of Symbicort. Sometimes, these side effects will ease or disappear after the body becomes acclimated to the medication. Tell your doctor if they persist or worsen.

There are also several serious side effects of Symbicort that can indicate a complication or adverse reaction. According to the Mayo Clinic, these most frequently include shortness of breath, voice loss, tenderness of the face, and nasal or ear congestion. Fever, chills, and other flu-like symptoms also fall under this category. Other serious side effects of Symbicort include significant weight gain, cloudy urine, changes in appetite, wheezing, difficulty sleeping or other sleep abnormalities, and mood changes. In the event of an allergic reaction, side effects of Symbicort include hives, itchiness, and swelling of the face, mouth, or throat. Contact your doctor immediately if any of these complications develop.

Symbicort can also interact with certain other drugs and supplements. WebMD reports that MAO inhibitors and tricyclic antidepressants should not be taken while taking Symbicort. The drug natalizumab, used in the treatment of multiple sclerosis and Crohn’s disease, can have major interactions when taken with Symbicort.

Symbicort combines the corticosteroid budesonide and the bronchodilator formoterol to relieve symptoms of asthma and other lung diseases. The side effects of Symbicort can be wide-ranging and some are indicative of a serious reaction. Additionally, certain other drugs can worsen these side effects or otherwise interact with Symbicort. Before taking Symbicort, talk to your doctor about the risks involved and about any other drugs or supplements you are taking.


Budesonide and Formoterol (Inhalation Route). Mayo Clinic.

Symbicort Inhl. WebMD.

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