Monday, December 11

Chronic Kidney Disease

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Kidney failure is a disruption of the kidney to perform its functions optimally. In renal failure the kidneys ability to remove residual substances and excess fluid from the body will decrease.
Chronic renal failure is a condition in which both kidneys were damaged permanently and can not function properly.
Chronic renal failure is a clinical syndrome caused by decreased kidney function is chronic, progressive place, quite advanced and irreversible. This condition causes the body’s ability to maintain metabolic failure, and failure to maintain fluid and electrolyte balance, causing symptoms of uremia.
Uremia is a toxic kadaan caused kidney failure. uremia occurs when kidney function can not remove the urea out of the body that accumulate in the blood.
Increased levels of urea nitrogen compounds refers to the increase (urea, creatinine and uric acid) in renal failure. The cause of uremia were divided into three, namely:
1. Cause prarenal
Prarenal uremia occurs because the failure mechanism that worked before in glomerular filtration. The mechanisms include decreased blood flow to the kidneys, blood loss and dehydration.
2. The cause of renal
Uremia renal excretion of urea caused by interference. Acute renal failure can be caused by glomerulonephritis, malignant hypertension, nephrotoxic drugs or metals and renal cortical necrosis. Chronic renal failure caused by glomerulonephritis, pyelonephritis, diabetes mellitus, arteriosclerosis, amyloidosis, renal tubular disease and collagen-vascular disease.
3. Cause pascarenal
Pascarenal uremia due to urinary tract obstruction in the lower ureter, bladder and urethra that prevents urine excretion. Ureteric obstruction caused by the tumor, inflammation or surgical errors.

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