Rubella is a disease caused by a viral RNA togavirus class. Rubella is relatively harmless, but if the infection attack someone who is pregnant, can cause the formation of organs, and cause birth defects in babies conceived. This condition occurs because the replication of virus in fetal tissues that persist, affecting fetal growth and cause disability or other abnormalities. Rubella virus infection in pregnant women the second trimester, can cause abnormalities in the organs. Persistence of viral replication in the uterus can cause extensive abnormalities in the neonatal period. These disorders include:
1. Anemia hemolitika with extra medullary hematopoiesis
3. Interstitial nephritis
5. Interstitial pancreatitis
Rubella virus transmission is usually by air, having an incubation period of between eleven to fourteen days. The clinical features of rubella infection include:
8. Spots arise in the form of a typical exanthema namely centrifugal makulo papular, ranging from the upper chest, abdomen and extremities, usually disappears after three days.
To diagnose rubella infection is very difficult because the symptoms are not typical. Diagnosis is established when the rubella titer increased four times during the acute phase. Prenatal diagnosis is done by checking the existence of IgM from the blood of the fetus through CVS (chorionoc villus sampling) or kordosentesis. Response to prevent rubella infection is done by way of vaccination. Rubella vaccination via subcutaneous injection, by injecting the rubella virus is still alive and has been.