Bioinformatics is the application of computer technology for managing and analyzing biological data. The terms bioinformatics, computational biology, and sometimes, bioinformatics are used interchangeably to refer to interdisciplinary fields of study.
Which are closely linked and require the use or development of different techniques that include computer science, applied mathematics, statistics, computer science, artificial intelligence, chemistry, and biochemistry. Aimed at solving problems, analyzing data, and simulating systems and mechanisms.
The core of these techniques involves the use of computational resources to solve or investigate problems on a magnitude that exceeds human insight. Research in computational biology frequently converges with systems biology.
Major research efforts in these areas include sequence alignment, gene prediction, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression, protein-protein interactions, and modeling of evolution.
Online services in bioinformatics
The EBI classifies primary bioinformatics services into three segments:
– SSS (Sequence Search Services),
– MSA (Multiple Sequence Alignment)
– BSA (Biological Sequence Analysis).
The accessibility of such bioinformatics resources illustrate the practicality of internet based bioinformatics solutions. Which range from a set of tools that have an identical data format under an detached or web-based interface. In addition to integrative, circularized and extensible bioinformatics workflow management systems.
In essence, SOAP and REST-based interfaces were formulated for an assortment of bioinformatics applications enabling connections from different parts of the world. Using algorithms, data and computing resources running on servers situated thousands of miles away. As such users take advantage of this access without concern of financial and technical needs of maintaining these systems.
– Physiological modeling and computer simulation of organs
– Support for the creation of new drugs (structure prediction, interactions)
– Development of software for analysis and prediction of biological data (genomics, transcriptomics, proteomics, etc.)
– Software development for biology: (LIMS web interface, etc.)
– Research in the laboratory (biotech, pharmaceutical, etc.).
– Modeling of ecosystems or ecosystem processes (gene in ecological network)
– Support for the creation of genetically modified organisms (bacteria, plants, etc.)
– Support for the creation of testing and diagnostic systems for medical laboratories, blood centers including industrial control
– Creation, maintenance and development of data warehouses, etc.
Concepts and scope
As in the introduction, the terms bioinformatics, computational biology and biocomputing are often used as synonyms, appearing frequently in the undifferentiated basic literature in their common uses. However, there are shaped areas of application of each term.
Computational biology is the development and application of theoretical methods and data analysis, mathematical modeling and computer simulation techniques to the study of biological, behavioral and social.
Thus, bioinformatics have more to do with the information while computational biology would do with the hypothesis. Moreover, the term is often set in biocomputing current research biocomputers and, for example, T. Kaminuma defined as follows: Biocomputing is the construction and use of computers with components that act as biological or living organisms.